Daily Perricone» diabetes

Preserving Lean Muscle Mass

Dr. Perricone — Mon, 29 Jun 2009 17:38:06 +0000

As we age we gain body fat and lose muscle mass. Fortunately there are several key nutrients that help us preserve lean muscle mass, such as conjugated linoleic acid (CLA) and chromium.

Experts in the field of nutrition report that the general population of the United States is deficient in chromium–and it should come as no surprise that low levels of chromium are associated with type 2 diabetes and cardiovascular disease—both of which are endemic in developed countries.

In a placebo-controlled, cross-over study, Dr. Preuss and a team of researchers at Georgetown University Medical Center showed that overweight African-American women consuming 600 mcg of chromium as niacin-bound chromium trade name ChromeMate® for 8 weeks had a significant loss of body fat and sparing of muscle (lean body mass) compared with a prior placebo period of the same duration. Increased fat loss was also observed among women who were randomized to consume chromium first, followed by placebo, suggesting a carry-over effect of the supplementation on fat loss. No adverse effects were observed.

Studies have also been published noting that increased consumption of sugar (and related sweeteners) depletes our body stores of chromium, placing us at further risk for hyperglycemia and hyperinsulinemia (too much blood sugar, too much insulin).

In a perfect world, we would avoid refined sweeteners. Realistically we know that we all succumb to sugar’s siren song on occasion, therefore remember to make sure that you take a chromium supplement to prevent depleting your body’s stores of this important nutrient.

A Longer, Healthier Life, as easy as NBC

Dr. Perricone — Sat, 27 Jun 2009 16:50:20 +0000

For many years, researchers in the field of aging believed that the only way you could increase lifespan was by caloric restriction (CR). This is because low caloric intake will improve blood glucose levels and insulin sensitivity, thereby helping to prevent one of the most dangers pitfalls of aging, obesity, metabolic syndrome and diabetes. Recommend calorie deficits are approximately 250 – 500 calories, about 30% less food than we would normally eat. While this is an effective strategy, you won’t be incorrect when I state that is not overwhelmingly popular.

However, there is good news on the horizon. The nutritional supplement, niacin bound chromium (NBC) appears to produce similar effects when compared to caloric restriction.

Niacin Bound Chromium (NBC) for Life Extension
My colleague at Georgetown University’s School of Medicine, Dr. Harry Preuss, recently alerted me to very new and exciting findings. Animal studies found that chromium polynicotinate, also known as niacin-bound chromium (NBC) increased the average lifespan by twenty percent compared to animals taking a placebo. The NBC helps to lower the levels of circulating glucose (sugar) in the body. One of the reasons I advocate eliminating (as much as possible) sugar and simple starches from your diet is because high levels of circulating glucose in the body increase the presence of free radicals, which are the primary cause of metabolic disorders which can lead to diabetes. Scientists have repeatedly demonstrated that diabetes represents a premature form of aging, because of the damage caused by the excessively perturbed glucose-insulin system. This is really exciting news and one of the first strategies (other than caloric deprivation) shown to positively impact life-span

Chromium is a very important trace mineral that promotes normal insulin function and is essential for proper protein, fat and carbohydrate metabolism. As any anti-aging scientist well knows, elevated levels of insulin and blood sugar significantly accelerate cellular aging. Research now shows that the type of chromium known as NBC has a superior anti-aging and safety profile.

Extensive clinical and basic research utilizing a unique form of oxygen-coordinated niacin-bound chromium—generally known as chromium nicotinate or polynicotinate (trade name ChromeMate®) has shown that the niacin-bound form of chromium is the superior form (some forms have a worrisome profile, therefore I recommend utilizing the ChromeMate® brand for both safety and efficacy).

This form of NBC provides significant health benefits to those with diabetes and with metabolic syndrome and is, indeed, the most optimal form of chromium available as a dietary supplement.
The main benefits of NBC include:
• Promotion of proper insulin function and normal blood sugar levels
• Promotion of healthy blood cholesterol levels, normal blood pressure, and cardiovascular health
• Promotion of healthy body weight and lean body mass

Preserving Lean Muscle Mass
As we age we gain body fat and lose muscle mass. Fortunately there are several key nutrients that help us preserve lean muscle mass, such as conjugated linoleic acid (CLA) and chromium.

As always I welcome your comments and suggestions,

Nicholas Perricone, MD, FACN, CNS

In Full Swing—Secrets to a Longer, Healthier Life

Dr. Perricone — Wed, 24 Jun 2009 17:55:14 +0000

Scientists long ago established that exercise greatly reduces both the incidence and severity of age-related degenerative diseases. But we don’t just want to live longer; we want to extend the number of our healthy years. We want to stay fit and active with the capacity to enjoy life to its fullest. Gerontologists refer to this as our ‘health span’ – as opposed to our simple “life span” – and universally agree that exercise is a crucial component to extend and improve them both. The right exercise will strengthen our bones and muscles, improve and restore physical and emotional balance, relieve stress and improve physical, mental and emotional health.

Exercise will also significantly decrease the effects of what is known as “secondary aging”- the occurrence and severity of diseases associated with aging. In fact, it is these degenerative diseases from arthritis to Alzheimer’s that are often responsible for reducing both the life and the health span. Exercise is a key element in helping us to prevent disease and prolong our good health into our seventh, eighth, ninth decade and beyond. In recognition of this, I would like to tell you about a wonderful story headlined “102 Year-Old Golfer Scores Hole in One.” Elsie McLean, a golfer since the 1920’s set a new world record for the oldest woman, or man to hit a hole in one. “Well everybody wants a hole-in-one, and I said, ‘Why can’t I have a hole-in-one?’ I came within inches once,” Elsie told television station KNVN. She broke the age record of 101 set by Harold Stilson in 2001 at Deerfield Country Club in Florida. “For an old lady,” she said, “I still hit the ball pretty good.” She added.

Elsie not only enjoys a physically active lifestyle and fresh air through her love of golf, she also has friends to enjoy the game with—thereby avoiding two of the sorrows of advanced age, loneliness and isolation.

As always I welcome your comments and suggestions.

Nicholas Perricone, MD, FACN, CNS

Maitake Mushrooms Benefits for Weight Loss and Immune System

admin — Fri, 01 May 2009 02:19:56 +0000

In the northeastern woods of Japan and the United States grows a ruffly-looking, exotic fungus with exciting possibilities, both culinary and nutritional. Called maitake or hen of the woods mushrooms, their woodsy aroma, meaty texture, and rich flavor have long given them special status in Japanese cuisine. Now, research is showing that maitake have potential that goes far beyond the kitchen.

Traditional Chinese medicine credited maitake and other mushrooms with having medicinal powers for centuries, but in the last 30 years Japanese researchers have examined the specific ways mushrooms act within the body to fight disease and improve health. The results have been encouraging. According to various studies, maitakes appear to boost the immune system, reduce blood sugar levels, aid in lowering blood pressure, encourage weight loss, and help to both prevent and fight cancer.

Most of maitake’s health benefits seem to come from one main source. They contain beta-glucan, a polysaccharide compound thought to help the immune system by activating effector cells like macrophages, natural killer cells, and T cells. In addition to their role in general immunity, these types of antibodies also act against cancer. The polysaccharide is also thought to be the source of the mushroom’s ability to control blood sugar to help manage diabetes and improve weight loss.

On top of all that, maitakes are also a rich source of minerals like potassium, calcium and magnesium, B vitamins, and amino acids. With all that and the fact that they taste great too, it’s more than worth checking out these exotic fungal gems.

For an even easier way to harness the power of maitake mushrooms for your health, also check out Perricone MD’s Maitake Mushroom Extract.

A Better Night’s Sleep Makes for Better Health

admin — Wed, 15 Apr 2009 22:12:47 +0000

Here’s a riddle for good health: What makes you look and feel better without you actually doing anything at all? Need a hint? The more you chase it, the harder it can be to catch. The answer, of course, is sleep. Even though we’re born knowing how to sleep, most of us have felt the effects of poor quality or too little rest. Sleep is when our bodies repair themselves, and there’s evidence of a relationship between poor sleep and health problems like obesity, high blood pressure and diabetes.

Clearly good sleep is crucial to good health, but how can something so natural be so hard to do well? Popular sleep myths could be part of the problem. For example, many people think they can skimp on sleep during the work week and make it up by sleeping later on weekends. In reality, once you’ve developed a sleep deficit, you can’t get those lost hours back. More importantly, maintaining a consistent bedtime and waking schedule is one of the best things you can do to fall asleep easily and wake up refreshed.

Another myth that could be dragging you down is that people need less sleep as they get older. Adults need between seven and nine hours a night, regardless of age. Using the passage of another birthday as an excuse for only getting five hours a night is doing your body a disservice.

It may seem obvious, but a good night’s sleep starts in a well prepared room. Dark, cool, and quiet are the words to keep in mind. If your bedroom doesn’t fit the bill, invest in ear plugs, an eye mask, light blocking drapes, and a fan or white noise machine. Also, banish the computer and TV. Your bedroom should be a sanctuary away from your daily life.

It’s even more important to prepare yourself. Alcohol, caffeine, and food less than two hours before bed can all act as stimulants. Also, don’t expect to go from fully alert to asleep in an instant. Things like gentle yoga, meditation, breathing exercises, or a warm bath can all help to relax your muscles, calm your mind, and transition you to sleep.

Finally, if your best efforts still result in tossing, turning, and racing thoughts, don’t just lie there and count sheep. You can’t force yourself to fall asleep; trying too hard will only push rest farther away. Get up and do something relaxing like reading in another room until you feel calm enough to capture the benefits of a good night’s sleep.

For more ideas to help improve your sleep, check out Women’s Health.