Tag Archives: anti-inflammatories

10 Dirty Little Secrets about Body Fat

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10 Dirty Little Secrets about Body Fat

By Nicholas Perricone, MD, FACN, CNS

There are many reasons to embrace Paul McCartney’s suggestion for “No-meat Mondays/giving up meat one day a week.” In fact, unless you are eating 100% grass-fed meat, I recommend cutting back on overall meat intake. This is not just environmentally sound, it is sound from a health/longevity viewpoint. Grain-fed meat lacks CLA, which influences body fat and lean muscle, and the omega-3 fatty acids, which are as close to a health, beauty, longevity and weight-loss magic bullet that we can get. Grain-fed meat is also high in pro-inflammatory saturated fat. Consuming a lot of these saturated fats leads to the accumulation of visceral fat. 

The Truth about Body Fat

This past decade has seen a turnaround in the way scientists regard white adipose tissue—better known as body fat, perhaps two of the most dreaded words of our generation. There are many theories as to why so many people are afflicted with excess body fat today, when twenty or thirty years ago this was not the case. Instead of feeling guilty and depressed, we need a basic understanding about the danger of excess body fat and to be vigilant in our food choices. 

Dirty Little Secret #1

There are two types of fat: subcutaneous (under the skin) and visceral (found in the abdomen and surrounding vital organs). Visceral fat is of greater concern because it surrounds vital organs and is metabolized by the liver, which turns it into blood cholesterol. Consuming large amounts of saturated fat and/or performing little physical activity results in high stores of visceral fat.

Dirty Little Secret #2

We now know that body fat is not just an inert deposit of fat cells, stored as the result of overeating. These areas of fat storage are actually an active endocrine organ. 

Dirty Little Secret #3

Body fat produces hormones, as does our pancreas, thyroid, parathyroid, adrenals, pineal and pituitary glands and testes/ovaries, the organs that comprise the endocrine system. These secreted hormones, known as adipokines, can contribute to systemic, low-grade, chronic inflammation.

Dirty Little Secret 

Body fat, as a group of cells, communicates with other organ systems such as the brain, the liver, the bone marrow, skeletal muscle, the adrenal cortex, the sympathetic nervous system and the complete immune system.

Dirty Little Secret #5

This agglomeration of fat cells, now an active endocrine organ, has the unique distinction of being the only endocrine organ to send pro-inflammatory and destructive signals to all organ systems, creating a spectrum of problems in every organ system, from bone growth to sexual reproduction.

Dirty Little Secret #6

Body fat directly impacts appetite, energy and our immune system. 

Dirty Little Secret #7

Body fat itself controls how much body fat is going to be stored, and the greater the amount of fat we have stored, the greater its negative influence on the entire body—an extremely destructive, inflammatory influence.  

Dirty Little Secret #8

A large storage of body fat can be so overwhelming to the system that the fat cells have to secrete hormone-like substances to increase blood vessel growth necessary to feed the accumulation of fat. 

Dirty Little Secret #9

Blood vessel growth cannot keep up with the rapidly growing mass of fat cells, which then begin to become oxygen-starved. These oxygen-starved cells start releasing inflammatory chemicals to further trigger blood vessel growth. 

Dirty Little Secret #10

When we are obese, muscle is constantly converting to fat.


The Alpha and the Omega

The truth about body fat reads like a frightening 1950’s pulp science fiction story, like Steve McQueen’s memorable debut film, The Blob. But, in fact, an escape from this real-life horror story is detailed in The Perricone Weight Loss Diet (Ballantine Books 2006)—and although there is plenty of science, there is no fiction about it.  

This is why it is critical to take a powerful anti-inflammatory approach to dieting. It is the inflammatory chemicals, such as NfkB, that block the effects of insulin—whether it is to metabolize blood sugar or to nourish muscles with amino acids. 

Excess insulin and high blood sugar put a lock on body fat, ensuring that those fat cells are going nowhere. Avoid pro-inflammatory, sugary, starchy foods and beverages, body fat’s greatest allies. The high omega-3 content found in wild salmon, anchovies, sardines and other cold-water fish, along with fish oil capsules, will help eliminate this toxic fat. Their essential fatty acids have tremendous anti-inflammatory properties and are key in sensitizing our cells to insulin. Omega-3 EFAs also inhibit the production of the enzyme fatty acid synthase, which plays a role in the storage of calories as body fat. 

Alpha lipoic acid, a powerful anti-inflammatory nutrient, accelerates the removal of glucose from the bloodstream, improves insulin function and decreases insulin resistance, making its use another critical strategy in the fight against body fat.

Chromium is also critical in controlling and reducing body fat. It effectively lowers blood sugar and insulin levels—the key to the anti-inflammatory weight-loss diet. Chromium helps decrease inflammation, thereby unlocking the enzymes that aid in fat metabolization, while normalizing blood lipids such as triglycerides and cholesterol, increasing levels of the “good” HDL cholesterol and lowering total cholesterol and triglycerides, making it cardio-protective.

The general population of the United States is deficient in chromium—and low levels of chromium are associated with type 2 diabetes and cardiovascular disease. Studies have also been published noting that increased consumption of sugar depletes our body stores of chromium, placing us at further risk for hyperglycemia and hyperinsulinemia (too much blood sugar, too much insulin). 

As an active researcher, I welcome your comments and suggestions.

View PerriconeMD products to help manage weight

The Top 10 Weight Loss Supplements

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The Perricone Anti-Inflammatory Weight Loss Diet nutrients work in a special way to enhance loss of body fat, preserve muscle mass and regulate levels of blood sugar and insulin. They will also promote beautiful, healthy, youthful-looking skin.

  1. Alpha Lipoic Acid (ALA)
    Alpha lipoic acid, often referred to as ‘the universal antioxidant,” is a potent antioxidant and anti-inflammatory found naturally inside of the energy producing portion of the cell known as the mitochondria. Alpha lipoic acid enhances our ability to metabolize food into energy. ALA is a unique antioxidant because it is both fat and water soluble. This means it can go to all parts of the cell, including the lipid (fat) portions such as the cell plasma membrane, as well as the interior of the cell (known as the cytoplasm) where water soluble chemicals reside.

  2. DMAE (dimethylaminoethanol)
    DMAE is a naturally occurring nutritional substance with powerful anti-inflammatory properties; it is found in fish including wild Alaskan salmon, anchovies and sardines. DMAE is important in the production of neurotransmitters, which are essential in the communication from one nerve to another and between nerves and muscles. Taking DMAE as a supplement will not only improve your cognitive function by improving memory and problem-solving ability, it will help increase skin firmness and muscle tone—important for anyone on a weight loss or antiaging program.

  3. Glutamine
    Glutamine is the body’s most abundant amino acid. It plays an important role in keeping the muscles functioning properly and helps reduce muscle deterioration. Glutamine literally drives muscle-building nitrogen into the muscle cell where it is synthesized for growth. It is also converted into glucose when the body needs more energy. When the body is in a highly inflammatory state, it breaks down our muscle tissue to get the extra glutamine needed, resulting in muscle mass loss.

  4. Carnitine
    Carnitine and its derivative, acetyl L-carnitine, are two of the most important nutrients for weight loss. Carnitine is critical for energy formation and an active metabolism. Carnitine transports the fatty acids from our blood into the cell for this energy production. Thus, for carnitine to have optimum effect, we must have adequate essential fatty acids, such as omega 3’s, present in the diet.

  5. Acetyl L-carnitine
    Acetyl L-carnitine acts as an antioxidant, a natural anti-inflammatory that enhances the affects of the other antioxidant systems within the body. These anti-inflammatory properties protect the cell plasma membrane (the cell’s first line of defense) and prevent the conversion of arachidonic acid into pro-inflammatory chemicals. Although exercise will naturally increase our levels of acetyl L-carnitine, if we are obese, over thirty or have other health problems, it will not raise them to therapeutic levels, therefore supplementation is necessary.

  6. Coenzyme Q – 10
    Coenzyme Q-10, also called ubiquinone, is a powerful antioxidant/anti-inflammatory with many benefits for treating and preventing obesity. It acts similarly to acetyl L-carnitine in that it assists in energy production within the mitochondria. CoQ10 enhances the metabolism, giving us greater energy and endurance, a greater ability to lose body fat, preventing the energy decline seen in aging cells. CoQ10 also maximizes the burning of foods for fuel, helping to normalize fats in our blood.

  7. Conjugated Linoleic Acid (CLA)
    Conjugated linoleic acid is a fatty acid found in many of the foods we eat. At one time, beef and lamb were exceptional sources; however when their diet was changed from grass to grain, levels of CLA dramatically decreased in the meat and dairy products. CLA has powerful antioxidant/anti-inflammatory activity. It decreases body fat, especially in the area of the abdomen and helps block the absorption of fat and sugar into fat cells (adipocytes). It also helps the insulin receptors remain intact, thus increasing insulin sensitivity.

  8. Chromium
    Because Chromium is an essential nutrient for normal sugar and fat metabolism, it is critical in our effort to control and reduce excess body fat. Chromium supplementation effectively lowers blood sugar and insulin levels and can also increase levels of the ‘good’ HDL cholesterol. This lowers total cholesterol and triglycerides, thus playing a key role in regulating appetite, reducing sugar cravings, and lowering body fat.

  9. Gamma Linolenic Acid (GLA)
    Gamma linolenic acid is an important omega-6 essential fatty acid. The average American diet causes a deficiency of GLA because of the large amounts of trans fatty acids, sugar, red meats and dairy products. The body rapidly converts GLA into dihomo-gamma-linoleic acid, the precursor of prostaglandin E1, a powerful anti-inflammatory hormone-like compound that helps to regulate inflammation, blood pressure, and many other bodily processes.

  10. Maitake Mushroom Extract
    Studies show that maitake mushroom extract enhances insulin sensitivity for controlling blood sugar levels and may serve as a safe and reliable weight loss supplement—even without additional behavior modifications, such as decreased caloric intake and increased exercise. It is established as a powerful tool in preventing a dangerous quartet of metabolic imbalances that increase our risk of cardiovascular disease and diabetes called Metabolic Syndrome. Metabolic Syndrome consists of high blood pressure, elevated levels of insulin, excess weight (especially around the abdomen), and dyslipidemialow, or low levels of HDL (good) cholesterol, high levels of LDL (bad) cholesterol, and high levels of triglycerides. Read more about Maitake Mushroom benefits.

The 10 Sins of Skin Aging

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  1. Pro-Inflammatory foods (sugar and starches)
    Foods can be pro-inflammatory or anti-inflammatory. Avoid pro-inflammatory foods—these will promote wrinkles, a host of diseases, accelerate aging and cause the storage of body fat.  Eating pro-inflammatory foods such as sugary and starchy foods shows up on the skin as a loss of radiance, dark circles under the eyes, the loss of tone, puffiness, an increase in fine lines and wrinkles, the loss of facial contours and increased pore size.  These foods can also exacerbate acne, which is a systemic, inflammatory disease.   I am not exaggerating when I say that sugar can rob you of your youth, health, and beauty.

  2. Excessive exposure to the sun.
    Although we have all heard it a million times, excessive sun exposure will accelerate skin aging and cause skin cancer. We need to get some sun in order to absorb Vitamin D and keep our bones strong and healthy.  However, baking out in the hot sun at the beach or by the pool is very destructive to your skin, as well as to your immune system.  Excess sun exposure will cause photoaging, resulting in the following:

    Loss of skin elasticity
    Thinner, more translucent-looking skin
    Wrinkles
    Dry, rough, leathery skin
    Broken capillaries on the face
    Freckles,
    Liver spots on the face, back of hands, arms, chest and upper back
    Spots or blemishes on the lower legs and arms
    Skin Cancer

  3. Stress
    Of all the destructive, pro-inflammatory and pro-aging forces I have observed as a physician, nothing compares with the negative effects of stress. Stress causes certain hormonal changes in your body, which rapidly alters the function of the cells in your vital organs. Not surprisingly, these effects are reflected in the appearance of your skin.
     
    Stress causes the release of the hormone cortisol.  When we have large amounts of cortisol circulating in our blood streams for extended periods of time, it is extremely toxic. Our brain cells, or neurons, are extremely sensitive to the effects of cortisol. When it is circulating at a high level, cortisol causes brain cells to die. Excess cortisol can destroy your immune system, shrink other vital organs, decrease your muscle mass, and cause thinning of the skin, accelerating skin aging and wrinkling and making blood vessels under skin more prominent.

  4. Smoking Cigarettes and/or exposure to second hand smoke
    Cigarette smoke is highly damaging and aging to skin. When we inhale just one puff of a cigarette, over a trillion free radicals are produced in our lungs, which then trigger an inflammatory response that circulates throughout our body.  When we inhale tobacco smoke, the result is activation of white blood cells which line our arteries, causing an inflammatory response, predisposing us to heart disease. 
     

    In addition, there is a tremendous inflammatory response in all organs of the body —including the skin. Cigarette smoking depletes the skin of oxygen and vital nutrients including Vitamin C, critical in keeping skin youthful, moist and plumped up. Tobacco also acts as a vasoconstrictor, which means that it causes constriction of blood vessels. This reduces local blood flow to an area, and temporarily raises blood pressure.  When the blood flow is reduced to the skin it results in a gray, pallid, lifeless and unhealthy looking complexion. Smoking also causes dry, leathery looking skin, premature deep lines, wrinkles and loss of radiance.

  5. Excess Alcohol
    People generally think that alcohol is bad for the skin just because it dehydrates the body.  They incorrectly assume that increasing our water intake will counteract the problem.  Unfortunately, alcohol creates inflammation throughout the body including the skin, resulting in effects that far outlast dehydration.  The metabolites of alcohol are molecules known as aldehydes.  Aldehydes are destructive in that they cause damage to the cell plasma membrane, as well as other parts of the interior of the cell.
     

    Alcohol causes small blood vessels in the skin to widen, allowing more blood to flow close to the skin’s surface. This produces a flushed skin color and a feeling of warmth which can lead to broken capillaries on the face. The alcohol-induced dehydration also makes the skin more prone to fine lines and wrinkles.

    Dullness, enlarged pores, discoloration, sagging and lack of resilience are some of the short and longer term effects. Because alcohol alters blood flow to the skin, it will give you an unhealthy appearance that can last for days. An occasional glass of red wine can confer some health benefits for a number of reasons.  But as with everything from eating to exercise, moderation is the key.  Too much alcohol is highly destructive.

  6. Lack of sleep
    A good night’s sleep will ensure that you awake refreshed, looking radiant and youthful. Adequate sleep is vital to avoid eye area puffiness and maintain vibrant skin.  When we look at the hormone parameters during sleep, we find that sleep turns down the negative effects of cortisol and the “bad” neurotransmitters, like epinephrine and norepinephrine that can be elevated during stress. Growth hormone is released during sleep—and growth hormone is the youth hormone. The hormone melatonin is also released, which has a positive effect on the immune system and the skin. It is during sleep that we rebuild energy reserves and regenerate the body as our cells undergo a process of repair.  Studies also show that inadequate sleep leads to unwanted weight gain and a craving for fat laden and carbohydrate-heavy foods.
     

    People who exercise regularly enjoy improved sleep quality. They fall asleep more quickly, sleep more deeply, awaken less often, and sleep longer.

  7. Lack of Exercise
    There are mountains of studies proving that exercise can take off pounds, reduce incidence of heart disease, lower blood pressure, improve mood, solve sleep problems, and even cut risks of certain cancers.  Exercise will also ensure that you have beautiful skin.  Studies have indicated that exercise benefits the skin in much the same way it improves bone and muscle quality.  Without regular activity, bones become fragile and muscles atrophy.  When the skin of those who exercise regularly is examined under a microscope, the impact of their high fitness levels is clearly apparent.  The clear skin is thicker and has more and healthier collagen, the fibers that give the skin its strength and flexibility.  Exercise increases circulation and gives the skin a healthy and radiant glow.  As long as we use moderation and don’t overdo it, exercise of almost any kind has a powerful, positive, and anti-inflammatory effect on all our cells.

  8. Not eating enough protein
    This ongoing lack of protein is first notable in the face, as the features become soft looking.  The sharp definition, contoured cheekbones and that great jaw line all becomes blurred.  When the supply of protein is depleted, the body is then forced to feed upon itself.  This causes both tissue and muscle to breakdown. Protein cannot be stored in the body.  Because it is essential for cellular repair, the days that we don’t eat enough protein are the days that we are accelerating aging.

  9. Going fat free
    Healthy fats, especially omega 3 fatty acids and monounsaturated fat, have powerful anti-inflammatory effects improving skin’s moistness, texture, suppleness and smoothness.  We need good fats, such as those found in salmon, sardines and other cold water fish, extra virgin olive oil, nuts, seeds, avocado and açai (a Brazilian berry whose fatty acid ratio resembles that of olive oil).  These “good” fats will help us absorb nutrients from our vegetables and fruits, keep our cells supple, our skin glowing and wrinkle-free, our brains sharp and our mood upbeat.  We also need dietary fat to burn fat.

  10. Not drinking enough water
    Remember these key facts:  Water is important—If you do not drink water, your organs and cells cannot function.  You don’t have to overdo it—but if you don’t drink water, you cannot metabolize fat, nor can you flush wastes out of the cells.

    A dehydrated body provokes the development of aging, inflammatory compounds.  Water has great anti-inflammatory properties and will help you skin to be radiant, soft and supple—the key difference between a grape and raisin is water.

Try Perricone Cold Plasma to reduce the 10 signs of aging.

Top 10 Food Additives to Avoid

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  1. Hidden Sugars – Sugar comes in many forms. As you might assume, when we eat sugar it raises our blood sugar, and chronically high levels of sugar in the blood lead to the creation of the sugar bonds known as AGEs. Therefore it is very important to learn to recognize that there are many forms of sugar; in fact, the word “sugar” may or may not appear on the label at all. Look for: white sugar, cane sugar, brown sugar, confectioner’s sugar, invert sugar, raw sugar, beet sugar, turbinado sugar, corn syrup, high fructose corn syrup, dextrin, honey, maple, evaporated cane juice, malt, molasses, dextrose, fructose, sucrose, fruit juice concentrate, glucose, maltose.

  2. Artificial coloring – synthetic food dyes are unnecessary and are either toxic or are possible carcinogens, which means that they may promote cancer.

  3. Aspartame and all artificial sweeteners, including saccharin – these are dangerous excitotoxins with many negative effects.

  4. BHT and BHA – used to preserve fats and oils. Studies indicate that they may be carcinogenic.

  5. Brominated vegetable oil (BVO) – used in citrus flavored sodas and banned in more than 100 countries. It has been linked to damage in the major organ systems. Apparently the FDA does not require that it be listed on labels—so avoid any citrus flavored sodas(such as lemon or lime )as it is a good bet that BVO is included.

  6. Carrageenan – stabilizer and thickening agent; found in everything from ice cream to yogurt. May be a carcinogen and is linked to toxic hazards, including ulcers and cancer; In addition to suppressing immune function, carrageenan causes intestinal ulcers and inflammatory bowel disease in animals and some research indicates that carrageenan is associated with causing cancer in humans.

  7. Partially hydrogenated vegetable oils – these are the infamous trans fats directly linked to heart disease. The FDA published a paper stating that if people in the US stopped eating trans fat there would be 30,000 to 100,000 less deaths per year from CHD. Trans fats are also linked to breast and colon cancer, atherosclerosis, elevated cholesterol, depressed immune system, and allergies.

  8. Nitrates – form powerful cancer-causing agents in stomach; are found in smoked foods such as deli foods, cured meats, bacon, hot dogs, pepperoni, sausage, etc.

  9. MSG – A dangerous excitotoxin that may cause headaches, itching, nausea, nervous system and reproductive disorders, high blood pressure; pregnant, lactating mothers, infants, small children should avoid MSG; allergic reactions common; may be hidden in infant formula, low fat milk, candy, chewing gum, drinks, over-the-counter medications. Look for the following ingredients that contain MSG:

    Monosodium Glutamate Calcium Caseinate
    Hydrolyzed Vegetable Protein Sodium Caseinate
    Hydrolyzed Protein Yeast Extract
    Hydrolyzed Plant Protein Textured Protein (Including TVP)
    Plant Protein Extract Autolyzed Yeast
    Hydrolyzed Oat Flour Corn Oil

  10. Sulfites – can cause dangerous allergic reactions

Top Ten Superfoods for Weight Loss

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Here is a list of 10 Superfood groups to support a healthy weight loss and management program.

Super Food Groups
Each group is followed by a list of its primary functions in fighting weight gain, and the “STAR” and “Runners Up” foods in it.

  1. Rich Cold-Water Fish: Anti-inflammatory Omega-3 Fats
    TOP CHOICE:  Wild Alaskan Salmon
    Runners up:  Sablefish, Sardines, Anchovies, Herring, North Atlantic Mackerel, Trout, Tuna
  2. Favorite Fruits: Fiber, Anti-inflammatory Antioxidants, and other Phytonutrient Obesity-Fighters
    TOP CHOICES:  Apples, Grapefruit
    Runners up:  Berries, Pears, Peaches, Plums, Prunes, Cherries, Oranges
  3. “Back to Mono” Fruits: Fiber, Anti-inflammatory Antioxidants, Anti-inflammatory/Anti-Adiposity Fats, and other Phytonutrient Obesity-Fighters
    TOP CHOICE:  Avocado
    Runners up:  Olives, Coconut, Acai
  4. Hot Calorie Burners: Anti-inflammatory Antioxidants, Fiber, and other Phytonutrient Obesity-Fighters
    TOP CHOICE:  Chili Peppers
    Runners up:  Cayenne, chili powder
  5. Nuts and Seeds: Fiber, Anti-inflammatory Fats, and other Phytonutrient Obesity-Fighters
    TOP CHOICE:  Sesame Seeds and Sesame Butter (Tahini)
    Runners up:  Flaxseed, Walnuts, Cashews, Filberts, Pumpkin seed, Hemp seed
  6. Low-Fat Probiotic Dairy Foods: Nutriceutical Obesity-Fighters
    TOP CHOICE:  Low-Fat Yogurt
    Runners up: Low-Fat Kefir, Low-Fat Probiotic Milk
  7. Beans (legume family): Fiber, Anti-inflammatory Antioxidants and other Nutriceutical Obesity-Fighters
    TOP CHOICES:  Chana Dal (AKA Bengal gram dal or chholar dal), Lentils, Chickpeas, Mung Beans, Hummus (chickpea puree)
    Runners up:  Kidney Beans, Navy Beans, Pinto Beans, Black Beans
  8. Heritage Whole Grains: Fiber, Anti-inflammatory Antioxidants, and other Phytonutrient Obesity-Fighters
    TOP CHOICE:  Oats
    Runners up:  Hull-less Barley, Buckwheat
  9. Spicy Sugar-Stabilizers: Anti-inflammatory Antioxidants and other Phytonutrient Obesity-Fighters
    TOP CHOICES:  Cinnamon, Turmeric
    Runners up:  Cloves, Fenugreek
  10. Anti-inflammatory Vegetables: Fiber, Anti-inflammatory Antioxidants, and other Phytonutrient Obesity-Fighters
    TOP CHOICES:  Spinach, Kale, Chard, Collards, Root Vegetable Greens (Turnip, Mustard, Beet)
    Runners up:  Brussels Sprouts, Broccoli Florets, Broccoli Sprouts, Bell Peppers, Onion-Garlic (Allium) Family, Eggplant, Green or Red Cabbage (red has the higher anti-oxidant potential), Aromatic Culinary Herbs (e.g., parsley, mint, rosemary, thyme, basil, oregano), Lettuces (various types), Wheat and Barley Grasses, Blue-Green Algae and Spirulina

Perricone TV – Dr. Perricone On The Antioxidant Astaxanthin

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Do you know about the powerful antioxidant Astaxanthin (As-ta-Zan-thin). It’s also an anti-inflammatory as all antioxidants are anti-inflammatories. Here’s a quick overview from the Dr.

While found in some foods core to the anti-inflammatory diet, Astaxanthin can be found in our Skin & Total Body supplements:

Dr. Perricone Q&A – Cystic Acne and Hiradenitis Suppurativa

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Q: I am a 47-year-old woman with cystic acne; I’ve also suffered from hidradenitis suppurativa since a very young age. I have tried everything to no avail. Will your program help me?

A: Hidradenitis suppurativa is a chronic condition characterized by swollen, painful, inflamed lesions. As we know, cystic acne is a systemic inflammatory disease. To treat these two conditions I recommend that you closely follow the anti-inflammatory diet and take a dietary supplement that contains high levels of anti-inflammatories. I also recommend taking high-quality Omega-3 essential oil capsules three times per day. I recommend three brands: Perricone MD Omega-3; Optimum Health International’s M.D. Designs™ Norwegian Fish Oil; and Dr. Barry Sears OmegaRx Pharmaceutical Grade Fish Oil. Do not bother with discount fish oils – buy only the very best if you are serious about your treatment – your health and your looks.

Dr. Perricone Q&A – Body Acne

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Q: I have a bad case of “body type” acne on my inner thighs, and no medications seem to help. It is so bad that I have developed scarring from it, too.

A: Check with your dermatologist because this may not be a case of acne. It sounds like it may be a condition known as folliculitis, a general term that encompasses a group of skin conditions characterized by inflamed hair follicles. This inflammation may be caused by any number of things, including bacteria, infection, yeasts or fungi, and certain inflammatory skin diseases. Your dermatologist can determine the cause, and the best course of treatment. Over-the-counter treatments that might be helpful include topical alpha hydroxy acids containing glycolic acid. The scarring may actually be post-inflammatory hyper pigmentation. Applying a body toning lotion containing high levels of DMAE over the alpha hydroxy treatment may help the scarring / hyperpigmentation to fade.
You can help control the inflammation by on a cellular level by taking antioxidants and anti-inflammatories. For example, alpha lipoic acid (ALA) has powerful anti-inflammatory properties, which make it extremely valuable in the treatment of acne, and helps control both blood sugar and insulin. A rapid rise in blood sugar may produce a burst of inflammation that elevates insulin levels, which then affect many other hormones in the endocrine system, resulting in the formation of new acne lesions, not to mention the exacerbation of existing acne. When blood sugar is stabilized, insulin levels are more easily controlled. Alpha lipoic acid can control blood sugar by both sensitizing the cell to the effects of insulin and allowing the cell to better utilize blood sugar.

Dr. Perricone’s Top 10 Super Supplements – #5 – Acetyl L-Carnitine

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Super Supplement #5: Acetyl L-Carnitine
Like carnitine, acetyl-l-carnitine improves mitochondrial function, but to an even greater degree – because it can pass through the mitochondrial membrane. And like carnitine, acetyl-l-carnitine functions best when there is adequate dietary intake of omega-3 essential fatty acids. Both forms of carnitine are important in a weight loss regimen because they act as natural anti-inflammatories, they aid in transportation of fats into the mitochondria to be burned. They also enhance the sensitivity of insulin receptors, helping to decrease blood sugar and circulating levels of insulin. As we have learned, high levels of insulin are inflammatory and ‘lock’ our body fat in place.

DOSAGE RECOMMENDATION: 500 milligrams per day; however, individuals on a weight loss program may take up to 1500 milligrams of acetyl-carnitine daily.

Acetyl-l-Carnitine tips:
Carnitine and acetyl-l-carnitine are not to be used by people with bipolar disease (manic depression) or those who are susceptible to seizures (epilepsy) unless recommended by their physician.

Do not take acetyl-l-carnitine after 3 PM to prevent any difficulties with sleeping.

Exercise naturally increases our levels of acetyl-l-carnitine, however, if we are obese, over thirty, or have other health problems, it will not raise them to therapeutic levels; therefore supplementation is necessary.

Acetyl-l-carnitine may be taken with or without food.

For better utilization of fat for energy take omega 3 fish oil with carnitine.

Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management