Dr. Perricone’s 3-tiered philosophy for healthy aging and beautiful skin is the foundation of his holistic approach. This program consists of an anti-inflammatory diet, supplements and topicals. Each tier counteracts inflammation at the cellular level.
We invite you to listen as Dr. Perricone explains this innovative philosophy and offers solutions to that will change how you look and feel.
In this video, Dr. Perricone discusses the history and high-level anti-inflammatory benefits of the powerful antioxidant, DMAE, in supplements and skin care topicals. He also touches on the Brain-Beauty Connection.
In this video, Dr. Perricone discusses the value of Omega 3 and how to address the imbalance of fats we get versus the fats we need because of our modern diets. Omega 3 can help with brain function, is good for the heart, promotes general health and can help us achieve and maintain a healthy weight.
Today, the Connecticut attorney general will issue a warning about ubiquitous advertisements to purchase Acai supplements. Please note that while you might have seen his face and name associated with these ads, Dr. Perricone does not and has never endorsed ANY ACAI PRODUCT outside of our Perricone MD product, Super Berry Powder With Acai. These ads use Dr. Perricone’s name and image (as well as Oprah Winfrey and Dr. Oz) without his permission.
As is well-documented, Dr. Perricone is an advocate of the Acai berry and its multitude of health benefits, but he can not vouch for the quality, purity, and efficacy of any other product without extensive research into the formulations of these products.
For more details on the Connecticut attorney general’s actions, please read this article
Stress actually accelerates the rate at which cells age. Thus, controlling stress has significant anti-aging benefits. Chronic stress raises blood level insulin levels, increases risk of obesity and inter-abdominal fat and accelerates inflammatory gum disease. Elevated stress levels appear to raise cholesterol levels over the long-term.
But stress is something we have the power to control. With the right diet, supplements and exercise, and by focusing on positive emotions, we hold the key to a brighter, happier and healthier future.
Supplements to combat stress
Phosphatidylserine, Vitamin C Ester, Omega 3 Fish Oil, Rhodiola, Ginseng, Gingko Biloba
Stress elevates levels of the hormones insulin and cortisol which then act as inflammatory agents. Many of us suffer an excess of both of these hormones, the first from too many sugars and other carbohydrates in our diets, the second from too much stress and caffeine. Look for foods that are part of an anti-inflammatory diet and supplements rich in antioxidants like alpha lipoic acid supplements to help manage stress.
Q: I am a 47-year-old woman with cystic acne; I’ve also suffered from hidradenitis suppurativa since a very young age. I have tried everything to no avail. Will your program help me?
A: Hidradenitis suppurativa is a chronic condition characterized by swollen, painful, inflamed lesions. As we know, cystic acne is a systemic inflammatory disease. To treat these two conditions I recommend that you closely follow the anti-inflammatory diet and take a dietary supplement that contains high levels of anti-inflammatories. I also recommend taking high-quality Omega-3 essential oil capsules three times per day. I recommend three brands: Perricone MD Omega-3; Optimum Health International’s M.D. Designs™ Norwegian Fish Oil; and Dr. Barry Sears OmegaRx Pharmaceutical Grade Fish Oil. Do not bother with discount fish oils – buy only the very best if you are serious about your treatment – your health and your looks.
Q: I have a bad case of “body type” acne on my inner thighs, and no medications seem to help. It is so bad that I have developed scarring from it, too.
A: Check with your dermatologist because this may not be a case of acne. It sounds like it may be a condition known as folliculitis, a general term that encompasses a group of skin conditions characterized by inflamed hair follicles. This inflammation may be caused by any number of things, including bacteria, infection, yeasts or fungi, and certain inflammatory skin diseases. Your dermatologist can determine the cause, and the best course of treatment. Over-the-counter treatments that might be helpful include topical alpha hydroxy acids containing glycolic acid. The scarring may actually be post-inflammatory hyper pigmentation. Applying a body toning lotion containing high levels of DMAE over the alpha hydroxy treatment may help the scarring / hyperpigmentation to fade.
You can help control the inflammation by on a cellular level by taking antioxidants and anti-inflammatories. For example, alpha lipoic acid (ALA) has powerful anti-inflammatory properties, which make it extremely valuable in the treatment of acne, and helps control both blood sugar and insulin. A rapid rise in blood sugar may produce a burst of inflammation that elevates insulin levels, which then affect many other hormones in the endocrine system, resulting in the formation of new acne lesions, not to mention the exacerbation of existing acne. When blood sugar is stabilized, insulin levels are more easily controlled. Alpha lipoic acid can control blood sugar by both sensitizing the cell to the effects of insulin and allowing the cell to better utilize blood sugar.
A robust sex life enhances cellular health. Nature’s secrets for restoring a lost libido that delivers the added bonus of increased feelings of inner confidence, energy, endurance, stamina, well being and more.
Enjoying a healthy sex life offers many benefits including:
Improved Physical Well-Being, because sex:
• Improves Sleep
• Increases Fitness
• Cures Wrinkles! (well, maybe that’s a little strong – let’s say it helps)
A study conducted over ten years and involving more than 3,500 European and American women and men examined various factors associated with youthful appearance. A panel of judges viewed the participants through a one-way mirror and then guessed the age of each subject. Those women and men whose age was regularly underestimated by seven to 12 years were labeled “superyoung.” Among these superyoung people, one of the strongest correlates of youthful appearance was an active sex life.
And also promotes Psychological, Emotional, Social, and Spiritual Health, because it
• Improves overall quality of life
• Decreases risk of depression and suicide
• Reduces stress
• Increases self-esteem
• Enhances intimacy
• Improves social health
• Increases stability of relationships
• Heightens spirituality
However, as we age, our desire for sex can wane; this can be particularly true for women. With such a plethora of benefits, it is good to know that there are natural ways to help maintain a healthy sexual response as we age. These include many therapeutic strategies which act as mitochondrial rejuvenators to elevate mood, increase intellectual capacity, enhance immune system and improve sexual performance
Foods, Supplements and Botanicals
Maca to Enhance Fertility: Maca is the edible root of the Peruvian plant Lepidum meyenii, traditionally employed for its purported aphrodisiac and fertility-enhancing properties. Unlike Viagra whichs acts more on mechanical function, Maca acts more upon the libido, giving it a more natural and less potentially harmful methodology. Use of use of Maca is on the increase for a safe way to boost libido, enhance energy and improving sexual function.
Rhodiola: Rhodiola is plant with many powerful antioxidant properties. It also has sexual-stimulating effects and has been used to increase libido and to treat impotence
Tongkat Ali (Eurycoma longifolia): Tongkat Ali root contains a treasure trove of phytonutrients, including powerful antioxidants. Tongkat Ali boosts testosterone production, the primarily male hormone in both men and women, which may help to halt many of the signs of aging, increase libido and decrease body fat. Benefits include improved energy and sexual function, and it also has anti-viral, anti-malarial properties and helps fight high blood pressure and appears to possess considerable anti-cancer activity. What the Studies Show: A water soluble extract of Tongkat Ali not only increased testosterone, increased energy, and increased muscle mass, it also inhibited Sex Hormone Binding Globulin, (SHBG) allowing more free testosterone (the active, available testosterone in your body) to remain in the blood.
Foods: Salmon, shrimp, lobster, rainbow trout
Supplements: Astaxanthin Botanicals: Maca, Tongat Ali, Rhodiola Rosea
Q: I used to have normal-combination skin (face), with minor problems such as a few monthly breakouts and blackheads in the nose area. However, when I turned seventeen my breakouts increased and my skin became oilier. I tried a product containing 5% benzoyl peroxide and ended up with severe redness. My skin actually looked like it was burned, and I developed a rash of tiny pimples all over my face. So I stopped using everything except cleanser and toner for three days, but the rash and redness persisted. Now, three months later, the redness is gone but I still have the rash – and I’m still suffering from breakouts! To make matters worse, I live in a hot and humid climate, which seems to exacerbate the problem.
Benzoyl peroxide is popular ingredient in many over-the-counter acne medications, but as you have discovered, it can cause intense irritation in some cases. Read labels and avoid this ingredient in the future.
We need to approach your problem from the inside out. A three-tiered program (anti-inflammatory diet, supplements, and topicals) is critical in the fight against acne. Your first step should be to study the list of anti-inflammatory foods on our website and incorporate as many of them as possible into your daily diet. In addition, study the list of “bad” foods and avoid them. In your case, I strongly recommend you follow the Three Day Diet, but extend it to five days. You may find this will greatly alleviate the rash and the breakouts. In terms of topical treatment, I suggest you use a mild cleanser twice a day and DMAE toner pads three times a day. Don’t forget the right nutritional supplements, especially B vitamins and antioxidants (e.g., vitamins C, E, alpha lipoic acid, DMAE, and others available in the supplement section of our website.
Perricone Skin Care Products presents, our list of Top 10 Super Body Supplements.
Super Supplement # 1: Omega 3 Fish Oil
The incredible anti-inflammatory power of Omega-3 essential fatty acids found in the high fat fish and in fish oil can accomplish the following:
Reduce inflammation in all organ systems
Accelerate the loss of body fat
Elevate mood
Improve attention span
Stabilize blood sugar levels
Lower insulin levels
Create and maintain healthy serotonin levels
Stop the roller coaster effects of the carbohydrate highs and lows
Decrease appetite
Increase radiance to skin
Increase health of immune system
Increase energy levels
Decrease symptoms and severity of rheumatoid arthritis
Reduced symptoms and severity of chronic skin conditions such as eczema
Decreased cardiovascular risk
DOSAGE RECOMMENDATION: 3,000 mg per day of fish oil—however for those who need to lose significant weight I recommend three 1000 mg capsules 3 times per day with meals for a total of 9 capsules per day—this higher doses need to be approved by your physician.
Omega 3 Fish Oil Tips:
To avoid any dietary side effects from the omega 3 fish oils, (such as belching or stomach upset) divide the dose into three—for example, if you are taking 3,000 mg per day of fish oil, take one 1000 mg capsule with a meal three times per day.
Even though fish oil is basically a “food,” always check with your primary healthcare professional before embarking on any new body supplement. Any therapeutic intervention, even nutritional supplements, can be contraindicated in certain health conditions.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com)
Perricone MD Omega 3
Perricone MD Skin & Total Body
Super Supplement #2: Alpha Lipoic Acid (ALA)
Alpha lipoic acid is a superior anti-inflammatory, that penetrates all portions of the cell because it is both fat and water soluble. On a cellular level alpha lipoic acid exerts a wide variety of positive actions, all of them anti-inflammatory. In addition to its function as a powerful antioxidant/anti-inflammatory, alpha lipoic acid increases the body’s ability to take glucose into the cells. This increased sensitivity to insulin results in decreased blood sugar levels, accelerated weight loss.
DOSAGE RECOMMENDATIONS: Because alpha lipoic acid is found only in trace amounts in food, it must be taken as a supplement. Twenty-five to thirty milligrams is adequate for a young healthy person. I recommend anywhere from two to four hundred milligrams of alpha lipoic acid per day to my patients with specific health problems, or who are trying to lose body fat.
Alpha Lipoic Tips:
In the metabolic cycle, Alpha Lipoic Acid acts as a coenzyme in the production of energy by converting carbohydrates into energy (ATP).
ALA is the only antioxidant that can boost cellular levels of glutathione, the body’s most important antioxidant to overall health and longevity.
Take with meals.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com)
Perricone MD Alpha Lipoic Acid
Perricone MD Skin & Total Body
Perricone MD Health & Weight Management
Perricone MD Super Anti-oxidant
Super Supplement #3: Astaxanthin
Astaxanthin comes from the microalgae haematococcus pluvialis, found in abundance in arctic marine environments, and is a natural carotenoid (any of a class of yellow to red pigments, including the carotenes and the xanthophylls). Carotenoids are one of the most abundant molecules in the world and give nature its wide variety of colors—from carrots to flamingos. It is the most potent of all of the carotenoids—in fact it is ten times stronger than beta carotene and 100 times stronger than Vitamin E. Wild Alaskan salmon, lobster, rainbow trout, shrimp, crawfish, crab, and red caviar all owe their rich colors to their astaxanthin-rich diets. Astaxanthin is an exceptional anti-inflammatory, making it an important component of the anti-inflammatory diet. Its ability to protect muscles and increase physical endurance is a wonderful asset for everyone needing to start and maintain a regular exercise program.
DOSAGE RECOMMENDATION: 1-2 capsules, 2 mg each, per day. Look for the AstaReal™ trademark on your bottle of astaxanthin supplements for potency and purity.
Astaxanthin Tips:
Because astaxanthin has been proven to cross the blood brain barrier (see Carnitine below), it offers protection to the brain, the central nervous system and the eye.
It increases physical endurance and reduces muscle damage.
It reduces eye fatigue and improves visual acuity.
It provides wrinkle reduction by internal supplementation.
It reduces hyperpigmentation (better known as age spots).
It provides cytokine regulation; inhibiting the expression of inflammatory cytokines and chemokines.
It improves gastric health; and reduces infection/inflammation of H. pylori, spiral-shaped bacterium that can damage stomach and duodenal tissue, causing ulcers.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com)
Perricone MD Skin and Total Body
Super Supplement #4: Carnitine
Carnitine is a water soluble nutrient, very much like a B vitamin, that allows us to convert fat into energy. Carnitine and its derivative, acetyl L-carnitine (see below) are two of the most important nutrients for weight loss. However, for carnitine to have optimum effect, we must have adequate essential fatty acids (such as omega-3s) present in the diet. Carnitine is critical for energy formation and an active metabolism. Small amounts of carnitine can be obtained from foods such as meats and dairy products, but to get an adequate supply we must take carnitine supplements. Carnitine provides anti-aging benefits in that it enhances energy production in the cell, which is needed for cellular repair. Studies have also shown that carnitine helps prevent muscle loss during illness and also prevents the muscle loss associated with aging, known as sarcopenia. Carnitine is protective of liver function and enhances and protects the immune system, especially under stressful conditions.
DOSAGE RECOMMENDATION: The recommended dose for an adult under the age of 30 without ill health or obesity is approximately 500 milligrams per day. For those who are obese or have other health problems, the recommendation is 1500 to 2000 milligrams per day, taken in 500 milligram doses 3 or 4 times per day.
Carnitine Tips
For carnitine to have optimum effect, make sure you have an adequate omega-3 intake.
Do not take carnitine in the evening as it may interfere with sleep.
Carnitine may be taken with or without food.
For better utilization of fat for energy take omega 3 fish oil with carnitine.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Super Supplement #5: Acetyl L-Carnitine
Like carnitine, acetyl-l-carnitine improves mitochondrial function, but to an even greater degree – because it can pass through the mitochondrial membrane. And like carnitine, acetyl-l-carnitine functions best when there is adequate dietary intake of omega-3 essential fatty acids. Both forms of carnitine are important in a weight loss regimen because they act as natural anti-inflammatories, they aid in transportation of fats into the mitochondria to be burned. They also enhance the sensitivity of insulin receptors, helping to decrease blood sugar and circulating levels of insulin. As we have learned, high levels of insulin are inflammatory and ‘lock’ our body fat in place.
DOSAGE RECOMMENDATION: 500 milligrams per day; however, individuals on a weight loss program may take up to 1500 milligrams of acetyl-carnitine daily.
Acetyl-l-Carnitine tips:
Carnitine and acetyl-l-carnitine are not to be used by people with bipolar disease (manic depression) or those who are susceptible to seizures (epilepsy) unless recommended by their physician.
Do not take acetyl-l-carnitine after 3 PM to prevent any difficulties with sleeping.
Exercise naturally increases our levels of acetyl-l-carnitine, however, if we are obese, over thirty, or have other health problems, it will not raise them to therapeutic levels; therefore supplementation is necessary.
Acetyl-l-carnitine may be taken with or without food.
For better utilization of fat for energy take omega 3 fish oil with carnitine.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Super Supplement #6: Conjugated Linoleic Acid (CLA)
CLA is a fatty acid that is found in many of the foods we eat. At one time, beef and lamb were exceptional sources; however when their diet was changed from grass to grain, levels of CLA dramatically decreased in meat and dairy products. CLA is also a powerful aid in prevention and treatment of obesity. When taken in effective doses, CLA decreases body fat, especially in the area of the abdomen.
In addition to the antioxidant, anti-inflammatory and insulin-sensitizing actions of CLA, many studies show that CLA helps prevent muscle loss and weakness associated with aging and disease. This is one of the reasons CLA has long been a favorite supplement of athletes and body builders.
DOSAGE RECOMMENDATION: 1,000 mg, up to a maximum of 4,000 mg per day, taken in 1 or 2 doses.
CLA Tips:
When take with sesame seeds, the effects of CLA are enhanced.
The average diet provides no more than a gram (1000 mg) of CLA per day.
CLA may be taken with meals.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Super Supplement #7: Coenzyme Q10 (CoQ10)
Coenzyme Q10, also called ubiquinone, is a powerful antioxidant/anti-inflammatory with many benefits for treating and preventing obesity. It acts similarly to acetyl-l-carnitine in that it assists in energy production within the mitochondria. As we have learned, energy production declines as a cell ages, and that means that the cell’s ability to repair itself also declines. Working synergistically with acetyl-l-carnitine, carnitine, and alpha lipoic acid in the mitochondria, CoQ10 enhances the metabolism, giving us greater energy and endurance, and a greater ability to lose body fat, while preventing the energy decline seen in aging cells. CoQ10 also works synergistically with other antioxidants to elevate cellular levels of vitamins C, E, and glutathione and to help regulate blood sugar and enhance insulin sensitivity. CoQ10 also maximizes the burning of foods for fuel, helping to normalize fats in our blood.
DOSAGE RECOMMENDATION: I recommend a minimum of 30 milligrams per day. For those with health problems, under the supervision and recommendation of their physician, up to 300 milligrams per day. About three weeks of daily dosing are necessary to reach maximal serum concentrations of CoQ10.
CoQ10 Tips:
This supplement should be taken by anyone over 40, as tissue levels of CoQ10 decrease as people get older.
Although CoQ10 can be found in small amounts in fish such as sardines or salmon, as well as in nuts, I recommend supplementation for optimal anti-aging and weight loss benefits.
CoQ10 supplementation is of particular importance for women because they tend to have lower levels than their male counterparts.
CoQ10 is best taken with food.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Super Supplement #8: Chromium
Chromium is a critical nutrient in our effort to control and reduce excess body fat. By supplementing our diets with chromium, we can effectively lower blood sugar and insulin levels—the key to the anti-inflammatory weight loss diet.
DOSAGE RECOMMENDATION: I suggest 100 micrograms (mcg’s.) per day for the average person over 40 and up to 200 mcg’s per day for those on The Perricone Weight Loss Diet.
Chromium Tips
Chromium is an essential nutrient required for normal sugar and fat metabolism.
Chromium is important for energy production, and also plays a key role in regulating appetite, reducing sugar cravings, and lowering body fat.
Chromium absorption is made more difficult when milk, as well as when foods high in phosphorus are eaten at the same time.
Don’t take chromium with foods rich in phytic acid (unleavened bread, raw beans, seeds, nuts and grains and soy isolates) as this may decrease its absorption.
The recommended type of this supplement is Chromium Polynicotinate.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Perricone MD Super Anti-oxidant
Super Supplement #9: Gamma Linolenic Acid (GLA)
GLA is an important omega-6 essential fatty acid. GLA can increase the metabolic rate, an effect that causes the body to burn fat, resulting in weight loss. The average American diet causes a deficiency of GLA because of the large amounts of trans fatty acids, sugar, grain-fed red meats and dairy products that are consumed. GLA is very difficult to find in the diet, but is found in high amounts in borage, black current, and evening primrose oils.
DOSAGE RECOMMENDATION: 200 to 400 mg of GLA per day—one to two 1000 mg of Borage Oil.
GLA Tips:
Take GLA with meals to increase absorption.
GLA improves cell sensitivity to insulin, reducing our chance of developing diabetes, heart disease and excess body fat.
Borage oil is the richest supplemental source of GLA.
As with Omega-3 fish oil supplementation, results do not happen overnight and may take up to six months. Don’t let this dissuade you from adding this vital essential fatty acid to your diet as soon as possible.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Super Supplement #10: Dimethlaminoethanol (DMAE)
DMAE is a naturally occurring nutritional substance with powerful anti-inflammatory properties. DMAE is important in the production of neurotransmitters, especially acetylcholine, which is essential in the communication from one nerve to another and between nerves and muscles. In order for your muscles to contract, the message must be sent from your nerves to your muscles via acetylcholine. DMAE also has membrane stabilizing effects and can also help reduce body fat, most likely from its activity as a precursor to acetylcholine as well as its anti-inflammatory activity. Taking DMAE as a supplement will not only improve your cognitive function, it will help increase skin firmness and muscle tone.
DOSAGE RECOMMENDATION: My recommended dose is 50 to 100 milligrams per day. For certain therapeutic uses, such as lowering cholesterol, larger doses may be recommended. As always consult your physician.
DMAE Tips:
DMAE is a naturally occurring nutritional substance with powerful anti-inflammatory properties.
DMAE also has membrane stabilizing effects and can also help reduce body fat, most likely from its activity as a precursor to acetylcholine as well as its anti-inflammatory activity.
Taking DMAE as a supplement will not only improve your cognitive function, it will help increase skin firmness and muscle tone.
For optimum health, beauty and weight loss benefits, I recommend eating fish rich in DMAE, taking DMAE supplements as well as applying a topical lotion containing DMAE to face, neck and body.
It is thought that DMAE can make epilepsy and bipolar depression worse; thus, it is advised that those with these health problems avoid DMAE.
DMAE can also be over-stimulating for some people, perhaps causing muscle tension or insomnia, so individuals experiencing such difficulties are advised to discontinue use of DMAE.
Take with meals for optimum effect.
Perricone MD products with this super supplement (click below to shop PerriconeMD.com):
Perricone MD Health & Weight Management
Perricone MD Super Anti-oxidant
Perricone MD Skin & Total Body
Be sure to check out the latest advancement in Perricone products, Perricone MD Cold Plasma and No Foundation Foundation.
All of these products are endorsed with a Perricone discount to help manage the costs.